Title | Petrobactin, a photoreactive siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. |
Publication Type | Journal Article |
Year of Publication | 2002 |
Authors | Barbeau K, Zhang G, Live DH, Butler A |
Journal | J Am Chem Soc |
Volume | 124 |
Issue | 3 |
Pagination | 378-9 |
Date Published | 2002 Jan 23 |
ISSN | 0002-7863 |
Keywords | Benzamides, Gammaproteobacteria, Gas Chromatography-Mass Spectrometry, Nuclear Magnetic Resonance, Biomolecular, Petroleum, Siderophores, Spectrometry, Mass, Electrospray Ionization |
Abstract | Petrobactin is a bis-catecholate, alpha-hydroxy acid siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. The Fe(III)-complexed form of petrobactin is photoreactive in natural sunlight, mediated by the Fe(III)-citrate moiety. The reaction results in decarboxylation of the petrobactin ligand and reduction of Fe(III) to Fe(II). This report is one of the first to show the photoreactivity of Fe(III)-siderophores mediated by the ferric ion-alpha-hydroxy acid group. The demonstration of light-mediated decarboxylation of an Fe(III)-siderophore complex raises questions about a possible functional role for photoreactivity in siderophore-mediated iron uptake. |
Alternate Journal | J. Am. Chem. Soc. |
PubMed ID | 11792199 |
Grant List | GM38130 / GM / NIGMS NIH HHS / United States |