Siderophores of Marinobacter aquaeolei: petrobactin and its sulfonated derivatives.

TitleSiderophores of Marinobacter aquaeolei: petrobactin and its sulfonated derivatives.
Publication TypeJournal Article
Year of Publication2009
AuthorsHomann VV, Edwards KJ, Webb EA, Butler A
Date Published2009 Aug
KeywordsBenzamides, Magnetic Resonance Spectroscopy, Marinobacter, Molecular Structure, Siderophores, Spectrometry, Mass, Electrospray Ionization

Siderophores are low molecular weight, high-affinity iron(III) ligands, produced by bacteria to solubilize and promote iron uptake under low iron conditions. Two prominent structural features characterize the majority of the marine siderophores discovered so far: (1) a predominance of suites of amphiphilic siderophores composed of an iron(III)-binding headgroup that is appended by one or two of a series of fatty acids and (2) a prevalence of siderophores that contain alpha-hydroxycarboxylic acid moieties (e.g., beta-hydroxyaspartic acid or citric acid) which are photoreactive when coordinated to Fe(III). Variation of the fatty acid chain length affects the relative amphiphilicity within a suite of siderophores. Catecholate sulfonation is another structural variation that would affect the hydrophilicity of a siderophore. In addition to a review of the marine amphiphilic siderophores, we report the production of petrobactin disulfonate by Marinobacter aquaeolei VT8.

Alternate JournalBiometals
PubMed ID19357970
PubMed Central IDPMC3066035
Grant ListGM38130 / GM / NIGMS NIH HHS / United States
R01 GM038130-15 / GM / NIGMS NIH HHS / United States
R01 GM038130-16 / GM / NIGMS NIH HHS / United States