Title | Chrysobactin siderophores produced by Dickeya chrysanthemi EC16. |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Sandy M, Butler A |
Journal | J Nat Prod |
Volume | 74 |
Issue | 5 |
Pagination | 1207-12 |
Date Published | 2011 May 27 |
ISSN | 1520-6025 |
Keywords | Dipeptides, Molecular Structure, Pectobacterium chrysanthemi, Plant Diseases, Siderophores |
Abstract | The plant pathogen Dickeya chrysanthemi EC16 (formerly known as Petrobacterium chrysanthemi EC16 and Erwinia chrysanthemi EC16) was found to produce a new triscatecholamide siderophore, cyclic trichrysobactin, the related catecholamide compounds, linear trichrysobactin and dichrysobactin, and the previously reported monomeric siderophore unit, chrysobactin. Chrysobactin is comprised of L-serine, D-lysine, and 2,3-dihydroxybenzoic acid (DHBA). Trichrysobactin is a cyclic trimer of chrysobactin joined by a triserine lactone backbone. The chirality of the ferric complex of cyclic trichrysobactin is found to be in the Λ configuration, similar to Fe(III)-bacillibactin, which contains a glycine spacer between the DHBA and L-threonine components and is opposite that of Fe(III)-enterobactin, which contains DHBA ligated directly to L-serine. |
DOI | 10.1021/np200126z |
Alternate Journal | J. Nat. Prod. |
PubMed ID | 21545171 |
PubMed Central ID | PMC3126860 |
Grant List | GM38130 / GM / NIGMS NIH HHS / United States R01 GM038130-16 / GM / NIGMS NIH HHS / United States |