1970-1979

116. J.E. Dixon and T.C. Bruice. Dependence of the Primary Isotope Effect (kH/kD) on Base Strength for the Primary Amine Catalyzed Ionization of Nitroethane. J. Am. Chem. Soc. 1970, 92, 905.

117. T.C. Bruice; A.F. Hegarty; S.M. Felton; A. Donzel and N.G. Kundu. Aminolysis of Esters. IX. The Nature of the Transition States in the Aminolysis of Phenyl Acetates. J. Am. Chem. Soc. 1970, 92, 1370.

118. J.R. Maley and T.C. Bruice. Catalytic Reactions Involving Azomethines. XII. Transamination of 1-Methyl-3-hydroxy-4- formylpyridinium Chloride. Arch. Biochem. Biophys. 1970, 136, 187.

119. T.C. Bruice and J.R. Maley. Equilibrium Titration and pH-Stat Cell for a Cary 15 Spectrophotometer. Anal. Biochem. 1970, 34, 275.

120. B.M. Dunn and T.C. Bruice. Steric and Electronic Effects on the Neighboring General Acid Catalyzed Hydrolysis of Methyl Phenyl Acetals of Formaldehyde. J. Am. Chem. Soc. 1970, 92, 2410.

121. T.C. Bruice and A. Turner. Solvation and Approximation. Solvent Effects on the Bimolecular and Intramolecular Nucleophilic Attack of Carboxyl Anion on Phenyl Esters. J. Am. Chem. Soc. 1970, 92, 3422.

122. T.A. Giudici and T.C. Bruice. Synthesis of 2- Oxabicyclo[2.2.2]octane. J. Org. Chem. 1970, 35, 2386.

123. Bruice, Thomas C.. Proximity effects and enzyme catalysis. In Enzymes, 3rd Ed; P.D. Boyer; Ed.; Academic Press: New York, 1970; 2, Ch. 4, 217-79.

124. T.C. Bruice and A.F. Hegarty. Biotin-Bound CO2 and the Mechanism of Enzymatic Carboxylation Reactions. Proc. Natl. Acad. Sci. 1970, 65, 805.

125. T.A. Giudici and T.C. Bruice. Planarity as a Factor in Determining the Rate Constant and Mechanism of Acetal Hydrolysis. Chem. Commun. 1970, 690.

126. R.F. Pratt and T.C. Bruice. The Carbanion Mechanism (ElcB) of Ester Hydrolysis. III. Some Structure-Reactivity Studies and the Ketene Intermediate. J. Am. Chem. Soc. 1970, 92, 5956.

127. B.M. Dunn and T.C. Bruice. Further Investigation of the Neighboring Carboxyl Group Catalysis of Hydrolysis of Methyl Phenyl Acetals of Formaldehyde. Electrostatic and Solvent Effects. J. Am. Chem. Soc. 1970, 92, 6589.

128. A.F. Hegarty and T.C. Bruice, Acyl Transfer Reactions from and to the Ureido Functional Group. I. The Mechanisms of Hydrolysis of an O-Acylisourea (2-Amino-4,5-benzo-6-oxo-1,3- oxazine). J. Am. Chem. Soc.1970, 92, 6561.

129. A.F. Hegarty and T.C. Bruice. Acyl Transfer Reactions from and to the Ureido Functional Group. II. The Mechanisms of Aminolysis of an O-Acylisourea (2-Amino-4,5-benzo-6-oxo- 1,3-oxazine). J. Am. Chem. Soc. 1970, 92, 6568.

130. A.F. Hegarty and T.C. Bruice. Acyl Transfer Reactions from and to the Ureido Functional Group. III. The Mechanism of Intramolecular Nucleophilic Attack of the Ureido Functional Group upon Acyl Groups. J. Am. Chem. Soc. 1970, 92, 6575.

131. T.C. Bruice; P.G. Kury and D.M. McMahon. Chromophoric Lactones and the Mechanism of Chymotrypsin Action. J. Am. Chem. Soc. 1970, 92, 6674.

132. S.L. Walters and T.C. Bruice. Reactions of Tetranitromethane. II. The Kinetics and Products for the Reactions of Tetranitromethane with Inorganic Ions and Alcohols. J. Am. Chem. Soc. 1971, 93, 2269.

133. G.J. Kasperek and T.C. Bruice. Observations on an Oscillating Reaction. The Reaction of Potassium Bromate, Ceric Sulfate and a Dicarboxylic Acid. Inorg. Chem. 1971, 10, 382.

134. T. Maugh II and T.C. Bruice. The Role of Intramolecular Bifunctional Catalysis of Ester Hydrolysis in Water. J. Am. Chem. Soc. 1971, 93, 3237.

135. A.F. Hegarty; R.F. Pratt; T. Guidici and T.C. Bruice. Acyl Transfer Reactions from and to the Ureido Functional Group. IV. Neighboring Carboxyl Group General Acid Catalysis in the Hydrolysis of an O-Acylisourea (2-Amino-8-carboxy-4-oxo- 3,1,4-benzoxazine). J. Am. Chem., Soc. 1971, 93, 1428.

136. J.E. Dixon and T.C. Bruice. a Effects. III. The Reaction of Malachite Green with Primary Amines, Methoxylamine and Hydrazines. J. Am. Chem. Soc. 1971, 93, 3248.

137. T. Maugh II and T.C. Bruice. Hydrolysis and Aminolysis of O- Acylhydroxyquinolines. Intracomplex General Base-Catalyzed Aminolysis. J. Am. Chem., Soc. 1971, 93, 6584.

138. J.E. Dixon and T.C. Bruice. The a Effect. IV. Additional Observation on the a Effect Employing Malachite Green as Substrate. J. Am. Chem. Soc. 1971, 93, 6592.

139. T.C. Bruice, A. Brown and D.O. Harris. On the Concept of Orbital Steering in Catalytic Reactions. Proc. Natl. Acad. Sci. 1971, 68, 658.

140. B.M. Dunn and T.C. Bruice. Electrostatic Catalysis. IV. Intramolecular Carboxyl Group Electrostatic Facilitation of the A-l-Catalyzed Hydrolysis of Alkyl Phenyl Acetals of Formaldehyde. The Influence of Oxocarbonium Ion Stability. J. Am. Chem. Soc. 1971, 93, 5725.

141. R.F. Pratt and T.C. Bruice. Reactions of S-Acylisothioureas. I. S- to N-Acyl Migrations in S-Benzoylisothiobiotin and Analogs. Biochem. 1971, 10, 3178.

142. T.C. Bruice. Views on Approximation, Orbital Steering and Enzymatic and Model Reactions. Cold Spring Harbor Symposia on Quantitative Biology 1971, 36, 21.

143. T.C. Bruice and R.F. Pratt. An Intramolecular Acyl Transfer Reaction Limited by Substrate Isomerization. Chem. Commun. 1971, 20, 1259-61.

144. T.C. Bruice; L. Main; S. Smith and P.Y. Bruice. Preequilibrium Complex Formation and Nucleophilic Addition (and Its Position) As Factors in Flavin-Catalyzed Oxidations. J. Am. Chem. Soc. 1971, 93, 7327.

145. G.J. Kasperek and T.C. Bruice. The Mechanism of the Aromatization of Arene Oxides. J. Am. Chem. Soc. 1972, 94, 198.

146. R.F. Pratt and T.C. Bruice. Reactions of S-Acylisothioureas. II. Effects of Structure and Stereochemistry on the Rates of Hydrolysis, Thiol Elimination, and S and N Acyl Migration in Acylic Systems. J. Am. Chem. Soc. 1972, 94, 2823.

147. J.E. Dixon and T.C. Bruice. a Effect. V. Kinetic and Thermodynamic Nature of the a Effect for Amine Nucleophiles. J. Am. Chem. Soc. 1972, 94, 2052.

148. R. Goitein and T.C. Bruice. Effect of Transfer from Water to 1.0 M Water in Dimethyl Sulfoxide on the Reaction of Nucleophiles with Phenyl Esters. J. Phys. Comm. 1972, 76, 432.

149. G.J. Kasperek and T.C. Bruice. Intramolecular Catalysis in the Aminolysis of Thiol Esters. J. Org. Chem. 1972, 37, 1456.

150. T.C. Bruice and D.M. McMahon Nucleophilic Selectivity in Attack at Amide Bonds. Reactivity of Oxygen and Nitrogen Nucleophiles with N-Acetyldehydrophenylalanyl-L-proline Diketopiperazine. Biochem. 1972, 11, 1273.

151. H. Yagi; D.M. Jerina; G.J. Kasperek and T.C. Bruice. A Novel Mechanism for the NIH-Shift. (1,4-dimethylbenzene oxide isomerization/kinetic analysis/nonenzymatic additions/ microxomal oxidation/carcinogenesis). Proc. Natl. Acad. Sci. (USA) 1972, 69, 1985.

152. T.C. Bruice. Is "Orbital Steering" A New Concept? Nature 1972, 237, 335.

153. L. Main; G.J. Kasperek and T.C. Bruice. Isoalloxazine(Flavin)Dehydrogenation of Dimethyl trans-1,2-Dihydrophthalate. J. Chem. Soc., Chem. Commun. 1972, 14, 847-8.

154. G.J. Kasperek and T.C. Bruice. Differentiation Between the Concerted and Stepwise Mechanisms for Aromatization (NIH- Shift) of Arene Epoxides. J. Chem. Soc. Chem. Commun. 1972, 13, 784-5.

155. M. Brüstlein and T.C. Bruice. Demonstration of a Direct Hydrogen Transfer between NADH and a Deazaflavin. J. Am. Chem. Soc. 1972, 94, 6548.

156. S. Walters Jewett and T.C. Bruice. Reactions of Tetranitromethane. Mechanism of the Reaction of Tetranitromethane with Pseudo Acids. Biochem. 1972, 11, 3338.

157. L. Main; G.J. Kasperek and T.C. Bruice. Kinetics and Mechanism of the Isoalloxazine (Flavin) Dehydrogenation of Dimethyl Dihydrophthalates. Biochem. 1972, 11, 3991

158. G.J. Kasperek; T.C. Bruice; H. Yagi; N. Kaubisch and D.M. Jerina. Solvolytic Chemistry of 1,4-dimethylbenzene Oxide. A New and Novel Mechanism for the NIH-Shift. J. Am. Chem. Soc. 1972, 94, 7876.

159. R.F. Pratt and T.C. Bruice. The lack of an a Effect for Proton Abstraction from Carbon Acids. J. Org. Chem. 1972, 37, 3563.

160. L. Hevesi and T.C. Bruice. 5 vs. 4a-Addition to Isoalloxazine. J. Am. Chem. Soc. 1972, 94, 8277.

161. S. Shinkai and T.C. Bruice. Reduction of Pyridoxal Phosphate (and Analogs) by 1,4-Dihydropyrindine. J. Am. Chem. Soc. 1972, 94, 8258.

162. B.M. Dunn and T.C. Bruice. Physical Organic Models for the Mechanism of Lysozyme Action. In Advances in Enzymology; A. Meister; Ed.; Vol. 37; John Wiley and Sons, 1973; 1-60.

163. L. Hevesi and T.C. Bruice. Reaction of Sulfite with Isoalloxazines. Biochem. 1973, 12, 290.

164. P.Y. Bruice; G.J. Kasperek; T.C. Bruice; H. Yagi and D.M. Jerina. The Oxygen Walk as a Complementary Observation to the NIH Shift. J. Am. Chem. Soc. 1973, 95, 1673.

165. A. Brown and T.C. Bruice. Mechanism of Hydrolysis of Benzoyl Glucose Acylals. J. Am. Chem. Soc. 1973, 95, 1593.

166. S. Shinkai and T.C. Bruice. Model Reactions Which Establish a Facile Reduction of Pyridoxal Phosphate and Analogs by 1,4-Dihydropyridines. Biochem. 1973, 12, 1750.

167. T.C. Bruice; L. Hevisi and S. Shinkai. Mechanisms of Formation and Equilibria of 4a and 5 Adducts of an Isoalloxazine. Reaction of 10-(2',6'-Dimethylphenyl)-3-methylisoalloxazine- 6,8-disulfonate with Sulfite in Aqueous Media. Biochem. 1973, 12, 2083.

168. R. Job and T.C. Bruice. Chiral Recognition of a Prochiral (meso- Carbon) Centre by ?(-)436-a-1,1-2,9-diamino-4,7-diaza- decanecobaltate. J. Chem. Soc. Chem. Commun. 1973, 10, 332-3.

169. G.A. Rogers and T.C. Bruice. Isolation of a Tetrahedral Intermediate in an Acetyl Transfer Reaction. J. Am. Chem. Soc. 1973, 95, 4452.

170. G.J. Kasperek; P.Y. Bruice; T.C. Bruice; H. Yagi and D.M. Jerina. Multiple Pathways for Aromatization of 8,9-Indan Oxide. J. Am. Chem. Soc. 1973, 95, 6041.

171. S. Shinkai and T.C. Bruice. The Question of Covalent Intermediate Formation in the Flavine-Catalyzed Carbonyl to Carbinol Oxidation-Reduction Reaction. J. Am. Chem. Soc. 1973, 95, 7526.

172. J.E. Dixon and T.C. Bruice. Comparison of the Rate Constants for General Base Catalyzed Prototropy and Racemization of the Aldimine Species Formed from 3-Hydroxypyridine-4- carboxaldehyde and Alanine. Biochem. 1973, 12, 4762.

173. D.L. Elliot and T.C. Bruice. Evidence for an Intermediate Adduct in the Ethylenediaminetetraacetic Acid Mediated Photoreduction of Flavines. J. Am. Chem. Soc. 1973, 95, 7901.

174. R.C. Job and T.C. Bruice. Chiral Recognition of Prochiral Centers. The (2S,9S)-2,9-Diamino-4,7-diazadecanecobalt(III) Mediated Decarboxylation of Aminoalkylmalonic Acids. J. Am. Chem. Soc. 1974, 96, 809.

175. R.F. Atkinson and T.C. Bruice. Ring Strain and General Acid Catalysis of Acetal Hydrolysis Lysozyme Catalysis. J. Am.Chem. Soc. 1974, 96, 819.

176. D.M.E. Reuben and T.C. Bruice. Relative Nucleophilicity of Thiols and Glutathione Towards Benzene Oxide. J. Chem. Soc. Chem. Commun. 1974, 3, 113-14.

177. G.A. Rogers and T.C. Bruice. Control of Modes of Intramolecular Imidazole Catalysis of Ester Hydrolysis by Steric and Electronic Effects. J. Am. Chem. Soc. 1974, 96, 2463.

178. G.A. Rogers and T.C. Bruice. Synthesis and Evaluation of a Model for the So-Called "Charge-Relay" System of the Serine Esterases. J. Am. Chem. Soc. 1974, 96, 2473.

179. G.A. Rogers and T.C. Bruice. The Mechanisms of Acyl Group Transfer from a Tetrahedral Intermediate. J. Am. Chem. Soc. 1974, 96, 2481.

180. S.B. Smith; M. Brüstlein and T. C. Bruice. Electrophilicity of the 8 Position of the Isoalloxazine (Flavine) Ring System. Comment on the Mechanism of Oxidation of Dihydroisoalloxazine. J. Am. Chem. Soc. 1974, 96, 3696.

181. J.D. Richardson,; T.C. Bruice; S.M. Waraszkiewicz and G.A. Berchtold. Aromatization of 4-Carboxybenzene Oxide. J. Org.Chem. 1974, 39, 2088.

182. T.C. Bruice and I. Oka. Nucleophilic Displacements upon Phenyl Esters in Which the Direct Relationship between Basicity of the Leaving Group and Rate Is Determined by Ground State Conformations. A Question of Concerted Catalysis in the Hydrolysis of Hexachlorophene Esters. J. Am. Chem. Soc. 1974, 96, 4500.

183. P.Y. Bruice and T.C. Bruice. Intramolecular General Base Catalyzed Hydrolysis and Tertiary Amine Nucleophilic Attack vs. General Base Catalyzed Hydrolysis of Substituted Phenyl Quinoline-8- and -6-carboxylates. J. Am. Chem. Soc. 1974, 96, 5523.

184. P.Y. Bruice and T.C. Bruice. Aminolysis of Substituted Phenyl Quinoline-8- and -6-Carboxylates with Primary and Secondary Amines. Involvement of Proton-Slide Catalysis. J. Am. Chem. Soc. 1974, 96, 5533.

185. D. Clerin and T.C. Bruice. A Kinetic Study of the Fate of a Covalent Intermediate of the Type Proposed to be Involved in Flavin Catalysis. J. Am. Chem. Soc. 1974, 96, 5571.

186. J.P. Glusker; H.L. Carrell; R. Job and T.C. Bruice. Mechanism for Chiral Recognition of a Prochiral Center and for Amino Acid Complexation to a Cobalt(III) Tetramine. The Crystal Structure, Absolute Configuration, and Circular Dichroism of ?(-)436-ß2- [(2S,9S)-2,9-Diamino-4,7-diazadecanecobalt(III) aminomethylmalonate] Perchlorate Monohydrate. J. Am. Chem. Soc. 1974, 96, 5741.

187. P.Y. Bruice; T.C. Bruice; H.G. Selander; H. Yagi and D.M. Jerina. Comparative Mechanisms of Reaction of K-Region and Non-K- Region Arene Oxides of Phenanthrene. J. Am. Chem. Soc. 1974, 96, 6814.

188. S. Shinkai; T. Kunitake and T.C. Bruice. The Importance of 1,2- Enediols in the Reduction of Lumiflavin by a-Ketols. J. Am.Chem. Soc. 1974, 96, 7140.

189. I. Yokoe and T.C. Bruice. Oxidation of Thiophenol and Nitroalkanes by an Electron Deficient Isoalloxazine. J. Am. Chem. Soc. 1975, 97, 450.

190. T.C. Bruice; R. Maskiewicz and R. Job. The Acid-Base Properties, Hydrolytic Mechanism and Susceptibility to O2 Oxidation of Fe4S4(SR)4-2 Clusters. Proc. Natl. Acad. Sci. (USA) 1975, 72, 231.

191. S.B. Smith and T.C. Bruice. Mechanisms of Isoalloxazine (Flavine) Hydrolysis. J. Am. Chem. Soc. 1975, 97, 2875.

192. R.F. Williams; S. Shinkai and T.C. Bruice. Radical Mechanisms for 1,5-Dihydroflavin Reduction of Carbonyl Compounds. Proc. Natl. Acad. Sci. (USA) 1975, 72, 1763.

193. R. Maskiewicz; T.C. Bruice and R.G. Bartsch. The Acid-Base Properties and Kinetics of Dissolution of the Fe4S4 Cores of Chromatium Ferredoxin and High Potential Iron Protein. Biochem. Biophys. Res. Commun. 1975, 65, 407.

194. R.C. Job and T.C. Bruice. Iron-sulfur Clusters II: Kinetics of ligand exchange studied on a water-soluble Fe4S4(SR)4n- cluster. Proc. Natl. Acad. Sci. (USA) 1975, 72, 2478.

195. T.C. Bruice and Y. Yano. Radical Mechanisms for 1,5-Dihydro-5- methylflavine Reduction of Carbonyl Compounds. J. Am. Chem. Soc. 1975, 97, 5263.

196. D.M. Johnson and T.C. Bruice. Nucleophilic Catalysis of the Aromatization of an Arene Oxide. The Reaction of Trimethylamine with 4-Carbo-tert-butoxybenzene Oxide. J. Am. Chem. Soc. 1975, 97, 6901.

197. D.M.E. Reuben and T.C. Bruice. Reaction of Thiol Anions with Benzene Oxide and Malachite Green. J. Am. Chem. Soc. 1976, 98, 114.

198. P.Y. Bruice and T.C. Bruice. The Lack of Concertedness in the General Acid-Base Catalysis of the Enolization of Oxalacetic Acid. A Case for Stepwise Nucleophilic General Base Catalysis. J. Am. Chem. Soc. 1976, 98, 844.

199. P.Y. Bruice; T.C. Bruice; P.M. Dansette; H.G. Selander; H. Yagi and D.M. Jerina. Comparison of the Mechanisms of Solvolysis and Rearrangement of K-Region vs. Non-K-Region Arene Oxides of Phenanthrene. Comparative Solvolytic Rate Constants of K- Region and Non-K-Region Arene Oxides. J. Am. Chem. Soc. 1976, 98, 2965.

200. P.Y. Bruice; T.C. Bruice; H. Yagi and D.M. Jerina. Nucleophilic Displacement on the Arene Oxides of Phenanthrene. J. Am. Chem. Soc. 1976, 98, 2973.

201. P.Y. Bruice and T.C. Bruice. Modes of Acid Catalysis in the Aromatization of Arene Oxides. J. Am. Chem. Soc. 1976, 98, 2023.

202. C. Kemal and T.C. Bruice. Simple synthesis of a 4a-hydroperoxy adduct of a 1,5-dihydroflavin: Preliminary studies of a model for bacterial luciferase. Proc. Natl. Acad. Sci. (USA) 1976, 73, 995.

203. T.C. Bruice. Models and Flavin Catalysis. Progress in Bioorganic Chemistry, Vol. 4; E.T. Kaiser; Ed.; Wiley and Sons, 1976; 1-87.

204. C. Kemal and T.C. Bruice. The Chemistry of an N5-Methyl-1,5- dihydroflavin and Its Aminium Cation Radical. J. Am. Chem. Soc. 1976, 98, 3955.

205. T.C. Bruice. Some Pertinent Aspects of Mechanism as Determined with Small Molecules. Ann. Rev. Biochem. 1976, 45, 331.

206. M.A. Wells; G.A. Rogers and T.C. Bruice. Intramolecular Hydrolysis of a Methyl Ester by Substrate Bound Metal Hydroxide. J. Am. Chem. Soc. 1976, 98, 4336.

207. T.C. Bruice. Some Physical Organic Studies Dealing with Flavin Catalysis. Flavins Flavoproteins, Proc. Int. Symp., 5th 1976, Meeting Date 1975, 244-260.

208. T.C. Bruice and P.Y. Bruice. Solution Chemistry of Arene Oxides. Acc. Chem. Res. 1976, 9, 378.

209. R.F. Williams and T.C. Bruice. The Kinetics and Mechanisms of 1,5-Dihydroflavin Reduction of Carbonyl Compounds and Flavin Oxidation of Alcohols. 2. Ethyl Pyruvate, Pyruvamide and Pyruvic Acid. J. Am. Chem. Soc. 1976, 98, 7752.

210. T.C. Bruice and J.P. Taulane. The Kinetics and Mechanisms of 1,5-Dihydroflavin Reduction of Carbonyl Compounds and Flavin Oxidation of Alcohols. 3. Oxidation of Benzoin by Flavin and Reduction of Benzil by 1,5-Dihydroflavin. J. Am. Chem. Soc. 1976, 98, 7769.

211. R.F. Williams; S.S. Shinkai and T.C. Bruice. Kinetics and Mechanisms of the 1,5-Dihydroflavin Reduction of Carbonyl Compounds and the Flavin Oxidation of Alcohols. 4. Interconversion of Formaldehyde and Methanol. J. Am. Chem. Soc. 1977, 99, 921.

212. C. Kemal; T.W. Chan and T.C. Bruice. Chemiluminescent reactions and electrophilic oxygen donating ability of 4a- hydroperoxyflavins: General synthetic method for the preparation of N5-alkyl-1,5-dihydroflavins. Proc. Natl. Acad. Sci. (USA) 1977, 74, 405.

213. T.W. Chan and T.C. Bruice. One and Two Electron Transfer Reactions of Glucose Oxidase. J. Am. Chem. Soc. 1977, 99, 2387.

214. M.A. Wells and T.C. Bruice. The Nucleophilicity of Metal Bound Hydroxide Mechanisms of Displacement on Esters and Transesterification Involving the Metal-Acyl Anhydride Bond. In Metal-Ligand Interactions in Organic Chemistry and Biochemistry Part 2; B. Pullman and N. Goldblum; Eds.; D. Reidel Publishing Company: Dordrecht-Holland, 1976; 273-284.

215. H.L. Carrell; J.P. Glusker; R. Job and T.C. Bruice. A Synthetic Tetranuclear Iron-Sulfur Complex with Ionized Side Chains: The Crystal Structure of (Fe4S4(S(CH2)2COO)4)6- .(NA5.N(C4H9)4)6+.5C5H9NO. J. Am. Chem. Soc. 1977, 99, 3683.

216. R. Maskiewicz and T.C. Bruice. Kinetic Study of the Dissolution of Fe4S42- -Cluster Core Ions of Ferredoxins and High Potential Iron Protein. Biochem. 1977, 16, 3024.

217. A.R. Becker; D.J. Richardson and T.C. Bruice. Amine Catalysis and Spontaneous and Specific Acid Catalyses of the Dienone-Phenol Rearrangement. J. Am. Chem. Soc. 1977, 99, 5058.

218. M.A. Wells and T.C. Bruice. Intramolecular Catalysis of Ester Hydrolysis by Metal Complexed Hydroxide Ion. Acyl Oxygen Bond Scission in Co2+ and Ni2+ Carboxylic Acid Complexes. J. Am. Chem. Soc. 1977, 99, 5341.

219. T.C. Bruice; T.W. Chan; J.P. Taulane; I. Yokoe; D.L. Elliott; R.F. Williams and M. Novak. Changes in the Chemistry of an Isoalloxazine Brought About by Substitution at the 7 and 8 Positions by a Strongly Electronegative Substituent. J. Am. Chem. Soc. 1977, 99, 6713.

220. R.L. Chan and T.C. Bruice. The Chemistry of an Electron- Deficient 5-Deazaflavin. 8-Cyano-10-methyl-5- deazaisoalloxazine. J. Am. Chem. Soc. 1977, 99, 6721.

221. C. Kemal and T.C. Bruice. Chemiluminescence Accompanying the Decomposition of 4a-Flavin Alkyl Peroxide. Model Studies of Bacterial Luciferase. J. Am. Chem. Soc. 1977, 99, 7064.

222. C. Kemal; T.W. Chan and T.C. Bruice. Reactions of 3O2 with Dihydroflavins. 1. N3,5-Dimethyl-1,5-Dihydrolumiflavin and 1,5-Dihydroisoalloxazines. J. Am. Chem. Soc. 1977, 99, 7272.

223. T.W. Chan and T.C. Bruice. Reaction of Nitroxides with 1,5-Dihydroflavins and N3,5-Dimethyl-1,5-Dihydrolumiflavin. J. Am. Chem. Soc. 1977, 99, 7287.

224. M. Novak and T.C. Bruice. Oxidation of 9-Hydroxy- and 9- Methoxyfluorene Carbanions by Flavin. Proof of Radical Mechanism. J. Am. Chem. Soc. 1977, 99, 8079.

225. R. Maskiewicz and T.C. Bruice. Dependence of the rates of dissolution of the Fe4S4 clusters of chromatium vinosum high- potential iron protein and ferredoxin on cluster oxidation state. Proc. Natl. Acad. Sci. (USA) 1977, 74, 5231.

226. P.Y. Bruice; S.C. Wilson and T.C. Bruice. Inactivation of Glyceraldehyde-3-phospate Dehydrogenase and Yeast Alcohol Dehydrogenase by Arene Oxides. Biochem. 1978, 17, 1662.

227. A.R. Becker; J.M. Janusz; D.Z. Rogers and T.C. Bruice. Structural Features Which Determine the Carcinogenesis, Mutagenesis and the Rates of Acid- and Water-Mediated Solvolysis of and Nucleophilic Attack upon Diol Epoxides, Bay-Region and Non- Bay-Region Tetrahydro Epoxides, and K-Region and Non-K- Region Arene Oxides. J. Am. Chem. Soc. 1978, 100, 3244.

228. P.Y. Bruice and T.C. Bruice. Lack of Concertedness in the Catalysis of the Enolization of Oxaloacetic Acid by General Acids and Bases. Formation of a Carbinolamine Intermediate in the Tertiary Amine Catalyzed Enolization Reaction. J. Am. Chem. Soc. 1978, 100, 4793.

229. P.Y. Bruice and T.C. Bruice. Diethyl Oxaloacetate. Nonconcerted General Catalysis of Enolization, Tertiary Amine Catalyzed Enolization via an Addition-Elimination Mechanism, and General-Acid-Catalyzed Dehydration and Cleavage. J. Am. Chem. Soc. 1978, 100, 4802.

230. R. Maskiewicz and T.C. Bruice. Solvation as the Determining Factor for the Redox Potential for Fe4S4[S-(CH2)nCO2]6- -Cluster Ions. J. Chem. Soc., Chem. Commun. 1978, 16, 703-4.

231. T.W. Chan and T.C. Bruice. Importance of C4a- and N5-Covalent Adducts in the Flavin Oxidation of Carbanions. Biochem. 1978, 17, 4784.

232. R.L. Chan and T.C. Bruice. Characterization and One- and Two- Electron Redox Chemistry of 1,5-Dicarba-1,5- dideazaisoalloxazines (Flavins). J. Am. Chem. Soc. 1978, 100, 7375.

233. J.M. Janusz; A.R. Becker and T.C. Bruice. The Importance of Intramolecular Hydrogen Bonding on the Reactivity of Tetrahydro Diol Epoxides. J. Am. Chem. Soc. 1978, 100, 8269.

234. G. Tollin; R.L. Chan; T.R. Malefyt and T.C. Bruice. Some One Electron Reduction Products of Flavin Analogs: Cyanoisoalloxazines and Deazaisoalloxazines. Photochem. Photobiol. 1979, 29, 233-43.

235. C. Kemal and T.C. Bruice. Transfer of O2 from a 4a- Hydroperoxyflavin Anion to a Phenolate Ion. A Flavin- Catalyzed Dioxygenation Reaction. J. Am. Chem. Soc. 1979, 101, 1635.

236. S. Ball and T.C. Bruice. 4a-Hydroperoxyflavin N-Oxidation of Tertiary Amines. J. Am. Chem. Soc. 1979, 101, 4017.

237. D.Z. Rogers and T.C. Bruice. Comparative Chemistry of the Bay- and Non-Bay-Region Tetrahydro Epoxides of Phenanthrene. J. Am. Chem. Soc. 1979, 101, 4713.

238. R. Maskiewicz; D. Sogah and T.C. Bruice. Chemiluminescent Reactions of Lucigenin. 1. Reactions of Lucigenin with Hydrogen Peroxide. J. Am. Chem. Soc. 1979, 101, 5347.

239. R. Maskiewicz; D. Sogah and T.C. Bruice. Chemiluminescent Reactions of Lucigenin. 2. Reactions of Lucingenin with Hydroxide Ion and Other Nucleophiles. J. Am. Chem. Soc. 1979, 101, 5355.

240. A.R. Becker; J.M. Janusz and T.C. Bruice. Solution Chemistry of the syn- and anti-Tetrahydrodiol Epoxides, The syn- and anti- Tetrahydrodimethoxy Epoxides, and the 1,2- and 1,4- Tetrahydro Epoxides of Naphthaline. J. Am. Chem. Soc. 1979, 101, 5679.

241. A. Miller and T.C. Bruice. Oxidations by a 4a- Hydroperoxyisoalloxazine hindered in the 9a and 10a Positions. J. Chem. Soc., Chem. Comm. 1979, 20, 896-7.