Welcome to Zhang Group

        Independent Work (2014~)


Zhixun Wang†, Corrado Nicolini‡, Cedric Hervieu†, Yuk-Fai Wong†, Giuseppe Zanoni*‡, and Liming Zhang*† " Remote Cooperative Group Strategy Enables Ligands for Accelerative Asymmetric Gold Catalysis" J. Am. Chem. Soc. , ASAP[Link]


Xingguang Li†‡, Zhixun Wang†, Xu Ma†, Pei-nian Liu*‡, and Liming Zhang*† " Designed Bifunctional Phosphine Ligand-Enabled Gold-Catalyzed Isomerizations of Ynamides and Allenamides: Stereoselective and Regioselective Formation of 1-Amido-1,3-dienes" Organic Letters , 2017,19, 5744-5747 [Link]


Xiaoqing Li†‡ , Shengrong Liao†, Zhixun Wang†, and Liming Zhang*† " Ligand-Accelerated Gold-Catalyzed Addition of in Situ Generated Hydrazoic Acid to Alkynes under Neat Conditions" Organic Letters , 2017,19, 3687-3690 [Link]


Wen-Ting Wu, Liming Zhang, Shu-Li You " Recent Progress on Gold-catalyzed Dearmatization Reactions" Acta Chimica Sinica , 2017,75, 419-438 [Link]


Zhou Xu‡, Rongliang Zhai, Ting Liang, and Liming Zhang* "Efficient One-Pot Multifunctionalization of Alkynes En Route to α-Alkoxyketones, α-Thioketones and α-Thio Thioketals Via an Umpolung Strategy" Chemistry-A European Journal , 2017, ASAP [Link]


Zhixun Wang‡, Anguo Ying†‡, Zili Fan, Cedric Hervieu, and Liming Zhang* "Tertiary Amino Group in Cationic Gold Catalyst: Tethered Frustrated Lewis Pairs That Enable Ligand-Controlled Regiodivergent and Stereoselective Isomerizations of Propargylic Esters" ACS catalysis, 2017, 7 , 3676-3680 [Link]


Nan Li, Xiao-Lei Lian, Yu-Hui Li, Tian-Yi Wang, Zhi-Yong Han, Liming Zhang, and Liu-Zhu Gong "Gold-Catalyzed Direct Assembly of Aryl-Annulated Carbazoles from 2-Alkynyl Arylazides and Alkynes" Org. Let., 2016, 18 , 4178–4181 [Link]


Wen-Ting Wu, Liming Zhang and Shu-Li You "Catalytic asymmetric dearomatization (CADA) reactions of phenol and aniline derivatives " Chem. Soc. Rev., 2016, 45, 1570–1580 [Link]


Youliang Wang, Maxence Zarca, Liu-Zhu Gong, and Liming Zhang "A C–H Insertion Approach to Functionalized Cyclopentenones" J. Am. Chem. Soc., 2016, 138, 7516–7519 [Link]


Youliang Wang, Alexandre Genoux, Subir Ghorai, Hongyi Chen, Robert Todd, and Liming Zhang "Direct Conversion of Internal Alkynes into a-Iodoenones: One-Step CollaborativeIodination and Oxidation" Adv. Synth. Catal. 2016, 358, 1417 – 1420[Link]


Zhou Xu, Hongyi Chen, Zhixun Wang, Anguo Ying, and Liming Zhang "One-Pot Synthesis of Benzene-Fused Medium-Ring Ketones: Gold Catalysis-Enabled Enolate Umpolung Reactivity" J. Am. Chem. Soc., 2016, 138, 5515–5518 [Link]


Zhitong Zheng, Zhixun Wang, Youliang Wang and Liming Zhang "Au-Catalysed oxidative cyclisation" Chem. Soc. Rev., 2016, 45, 4448-4458 [Link]


Zhitong Zheng, Liming Zhang "C–H insertions in oxidative gold catalysis: synthesis of polycyclic 2H-pyran-3(6H)-ones via a relay strategy" Org. Chem. Front., 2015, 2, 1556-1560 [Link]


Hongyi Chen, Liming Zhang "A Desulfonylative Approach in Oxidative Gold Catalysis: Regiospecific Access to Donor-Substituted Acyl Gold Carbenes" Angew. Chem. Int. Ed., 2015, 54, 11775–11779 [Link]

82 Youliang Wang, Zhitong Zheng, Liming Zhang "Intramolecular Insertions into Unactivated C(sp3)–H Bonds by Oxidatively Generated β-Diketone-α-Gold Carbenes: Synthesis of Cyclopentanones" J. Am. Chem. Soc., 2015, 137, 5316–5319 [Link]


Youliang Wang, Liming Zhang "Recent Developments in the Chemistry of Heteroaromatic N-Oxides" Synthesis 2015, 47, 289-30 [Link]

80 Renhua Zheng, Youliang Wang, and Liming Zhang "Ruthenium-catalyzed rearrangement of propargyl sulfoxides: formation of α,β-unsaturated thioesters" Tetrahedron Lett. 2014, 56, 3144–3146[Link]

79 Kegong Ji, Zhitong Zheng, Zhixun Wang, and Liming Zhang "Enantioselective Oxidative Gold Catalysis Enabled by a Designed Chiral P,N-Bidentate Ligand" Angew. Chem. Int. Ed. 2014, 54, 1245-1249[Link]

78 Kegong Ji, Brendan D'Souza, Jon Nelson, Liming Zhang "Gold-catalyzed oxidation of propargylic ethers with internal C–C triple bonds: Impressive regioselectivity enabled by inductive effect" J. Organometallic Chem. 2014, 770, 142-145 [Link]

77 Youliang Wang, Zhitong Zheng, Liming Zhang "Ruthenium-Catalyzed Oxidative Transformations of Terminal Alkynes to Ketenes By Using Tethered Sulfoxides: Access to β-Lactams and Cyclobutanones" Angew. Chem. Int. Ed. 2014, 53, 9572-9576 [Link]

76 Zhitong Zheng, Mollie Touve, Josue Barnes, Norbert Reich and Liming Zhang "Synthesis-Enabled Probing of Mitosene Structural Space Leads to Improved IC50 over Mitomycin C" Angew. Chem. Int. Ed. 2014, 53, 9302-9305[Link]

75 Zhixun Wang, Yanzhao Wang and Liming Zhang "Soft Propargylic Deprotonation: Designed Ligand Enables Au-Catalyzed Isomerization of Alkynes to 1,3-Dienes" J. Am. Chem. Soc., 2014, 136, 8887–8890 [Link]

74 Gongde Wu, Renhua Zheng, Jonathan Nelson and Liming Zhang "One-Step Synthesis of Methanesulfonyloxymethyl Ketones via Gold-Catalyzed Oxidation of Terminal Alkynes: A Combination of Ligand and Counter Anion Enables High Efficiency and a One-Pot Synthesis of 2,4-Disubstituted Thiazoles" Adv. Synth. Catal. 2014, 356, 1229 [Link]

73   Yanzhao Wang, Zhixun Wang, Yuxue Li, Gongde Wu, Zheng Cao and Liming Zhang "A general ligand design for gold catalysis allowing ligand-directed anti-nucleophilic attack of alkynes" Nature Communications, 2014, 5, 3470 [Link]

72 Jiabin Li, Kegong Ji, Renhua Zheng, Jonathan Nelson and Liming Zhang "Expanding the horizon of intermolecular trapping of in situ generated α-oxo gold carbenes: efficient oxidative union of allylic sulfides and terminal alkynes via C–C bond formation" Chem. Commun., 2014, 50, 4130-4133 [Link]

71 Kegong Ji and Liming Zhang "A non-diazo strategy to cyclopropanation via oxidatively generated gold carbene: The benefit of a conformationally rigid P,N-bidentate ligand"Org. Chem. Front., 2014, 1, 34-38 [Link]

70 Zhitong Zheng, Hangfei Tu amd Liming Zhang "One-Pot Synthesis of Fused Pyrroles through a Key Gold-Catalysis-Triggered Cascade" Chem. Eur. J. 2014, 20, 2445-2448 [Link]

69 Liming Zhang "A Non-Diazo Approach to α-Oxo Gold Carbenes via Gold-Catalyzed Alkyne Oxidation" Acc. Chem. Res., 2014, 47, 877-888 [Link]

Independent Work







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Graduate Work


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contact us: Prof. Liming Zhang office: 1631E PSB-N tel: (805) 893-7392 Email: zhang@chem.ucsb.edu Lab: 1612A PSB-N
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