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Latest advances in Au/Ag/Pt catalysis for the Week

Aug 01- Aug 06


Well-Defined Chiral Gold(III) Complex Catalyzed Direct Enantioconvergent Kinetic Resolution of 1,5-Enynes

Catalytic Regio- and Enantioselective [4+2] Annulation Reactions of

Non-activated Allenes by a Chiral Cationic Indium Complex

Asymmetric syntheses of 8-oxabicyclo[3,2,1]octane and 11-oxatricyclo[]undecane from glycals

Jul 24-Jul 30


Cyclobutene vs 1,3-Diene Formation in the Gold-Catalyzed Reaction of Alkynes with Alkenes: The Complete Mechanistic Picture

Silver-Catalyzed Cascade 1,6-Addition/Cyclization of para-Quinone Methides with Propargyl Malonates: An Approach to Spiro[4.5]deca-6,9-dien-8-ones

Complex Annulations through Silver Carbenoid Intermediate: An Alternative Entry to Transformations of 1,2,3-Triazoles

Silver-Catalyzed Tandem C≡C Bond Hydroazidation/Radical Addition/Cyclization of Biphenyl Acetylene: One-Pot Synthesis of 6-Methyl Sulfonylated Phenanthridines

Jul 17-Jul 23


Chemoselective Asymmetric Intramolecular Dearomatization of Phenols with α-Diazoacetamides Catalyzed by Silver Phosphate

Inner-Sphere versus Outer-Sphere Coordination of BF4 in a NHC-Gold(I) Complex

Silver-Catalyzed Oxidative C(sp3)−P Bond Formation through C−C and P−H Bond Cleavage

Investigations on Gold-Catalyzed Thioalkyne Activation Toward Facile Synthesis of Ketene Dithioacetals

Photopromoted Entry to Benzothiophenes, Benzoselenophenes, 3H-Indoles, Isocoumarins, Benzosultams, and (Thio)flavones by Gold-Catalyzed Arylative Heterocyclization of Alkynes

Jul 03-Jul 09


Silver-Catalyzed Intramolecular C(5)–H Acyloxylation of 1,4-Di-substituted 1,2,3-Triazoles

Regioselective Domino Synthesis of 2-Alkylflavans via Hidden Brønsted Acid Catalysis

Jun 26 -Jul 02


Dual gold/photoredox-catalyzed bis-arylative cyclization of chiral homopropargyl sulfonamides with diazonium salts: rapid access to enantioenriched 2,3-dihydropyrroles

Silver-mediated radical 5-exo-dig cyclization of 2-alkynylbenzonitriles: synthesis of phosphinylated 1-indenones

Jun 19 -Jun 25

Xu Ma

Platinum(II) Dihalide Complexes with 9-Arsafluorenes: Effects of Ligand Modification on the Phosphorescent Properties

Synthesis and cytotoxicity studies of novel NHC–Gold(I) pseudohalides and thiolates

Synthesis, characterization and anti-proliferative activity of propylene linked bis-benzimidazolium salts and their respective dinuclear Silver(I)-N-heterocyclic carbene complexes

Access to silver-NHC complexes from soluble silver species in aqueous or ethanolic ammonia

Jun 12 -Jun 18


Stereoselective Synthesis of Tetrasubstituted Furylalkenes via Gold-Catalyzed Cross-Coupling of Enynones with Diazo Compounds

Gold-Catalyzed Oxidation Terminal Alkyne: An Approach to Synthesize Substituted Dihydronaphthalen-2(1H)-ones and Phenanthrenols

Gold(I)-catalyzed access to neomerane skeletons

Acenaphthoimidazolylidene Gold Complex-Catalyzed Alkylsulfonylation of Boronic Acids by Potassium Metabisulfite and Alkyl Halides: A Direct and Robust Protocol To Access Sulfones

Jun 05 -Jun 11


Access to Benzo[a]carbazoles and Indeno[1,2-c]quinolines by a Gold(I)-Catalyzed Tunable Domino Cyclization of Difunctional 1,2-Diphenylethynes

Cross-Coupling Reactions of Aryldiazonium Salts with Allylsilanes under Merged Gold/Visible-Light Photoredox Catalysis

Unraveling the Anion/Ligand Interplay in the Reaction Mechanism of Gold(I)-Catalyzed Alkoxylation of Alkynes

May 29 -Jun 04


Total Synthesis of Dictyodendrins by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles

Silver-Catalyzed Three-Component 1,1-Aminoacylation of Homopropargylamines: α-Additions for Both Terminal Alkynes and Isocyanides

Access to Tetronic Acids via Silver-Catalyzed CO2 Incorporation into Conjugated Ynones

Dual Gold Catalysis: Bidirectional Processes and Tandem sp3-C−H Insertion Reactions

May 22-May 28


Gold-Catalyzed Formal [3 + 2] Cycloaddition of Ynamides with 4,5-Dihydro-1,2,4-oxadiazoles: Synthesis of Functionalized 4-Aminoimidazoles

The Catalytically Lignan-Activation-Based Approach for the Synthesis of (epi)-Podophyllotoxin Derivatives

Synthesis of Polysubstituted Polycyclic Aromatic Hydrocarbons by Gold-Catalyzed Cyclization–Oxidation of Alkylidenecyclopropane-Containing 1,5-Enynes

Gold-Catalyzed Cadiot–Chodkiewicz-Type Cross-Coupling of Terminal Alkynes with Alkynyl Hypervalent Iodine Reagents: Highly Selective Synthesis of Unsymmetrical 1,3-Diynes

Gold(I)-Catalyzed Enantioselective Synthesis of Tetrahydrocarbazoles through Dearomative [4+2] Cycloadditions of 3/2-Substituted 2/3-Vinylindoles

Silver-mediated radical 5-exo-digcyclization of 2-alkynylbenzonitriles: synthesis of phosphinylated 1-indenones

May 15-May 21


Au-Catalyzed [2 + 3] Annulation of Enamides with Propargyl Esters: Total Synthesis of Cephalotaxine and Cephalezomine H

Metal Confinement through N-(9-Alkyl)fluorenyl-Substituted N-Heterocyclic Carbenes and Its Consequences in Gold-Catalysed Reactions Involving Enynes

General Entry into o-,o′-Heteroatom-Linked N-(Hetero)aryl-Imidazole Motifs by Gold-Catalysed Formal [3+2]-Dipolar Cycloaddition

Gold-catalyzed oxidative hydroacylation reactions of α-iminoalkynes with aldehydes and O2

α-Diazo oxime ethers for N-heterocycle synthesis

May 08-May 14


Unmasking the Catalytic Activity of a Platinum Complex with a Lewis Acidic, Non-innocent Antimony Ligand

Uncovering Subtle Ligand Effects of Phosphines Using Gold(I) Catalysis

Phosphine-Scavenging Role of Gold(I) Complexes from Pd(PBu3)2in the Bimetallic Catalysis of Carbostannylation of Alkynes

The Power of Ferrocene, Mesoionic Carbenes, and Gold: Redox-Switchable Catalysis

May 01-May 07


Synthesis of Spiroketals by Synergistic Gold and Scandium Catalysis

A Heterogeneous Gold(I)-Catalyzed [2 + 2 + 1] Annulation of Terminal Alkynes, Nitriles, and Oxygen Atoms Leading to 2,5-Disubstituted Oxazoles

Alkynyl sulfoxides as α-sulfinyl carbene equivalents: gold-catalysed oxidative cyclopropanation

Formal Synthesis of (+)-Laurencin by Gold(I)-Catalyzed Intramolecular Dehydrative Alkoxylation

Silver(I) Catalyzed Intramolecular Cyclization of N-(2-(alk-1-yn-1-yl))-1H-Tetrazoles leading to the formation of N-cyano-2-substituted Indoles under ambient conditions

Apr 24-Apr 30


Enantioselective Silver and Amine Co-catalyzed Desymmetrizing Cycloisomerization of Alkyne-Linked Cyclohexanones

Gold(I)-Catalyzed Cycloisomerization of ortho-(Propargyloxy)arenemethylenecyclopropanes Controlled by Adjacent Substituents at Aromatic Rings

Silver-Catalyzed Direct C6–H Arylation of Purines and Purine Nucleosides with Arylboronic Acids

Apr 17-Apr 23


Aldehydes as Carbon Radical Acceptors: Silver Nitrate-Catalyzed Cascade Decarboxylation and Oxidative Cyclization toward Dihydroflavonoid Derivatives

General Entry into o-,o’-Heteroatom-Linked N-(Hetero)aryl Imidazole Motifs by Gold-Catalysed Formal [3+2]-Dipolar Cycloaddition

Gold(III)-arene complexes by insertion of olefins into gold-aryl bonds

Apr 10-Apr 16


Gold(I)-Catalyzed [2 + 2 + 2] Cyclotrimerization of 1,3-Diarylpropargyl Acetals

Silver(I)-Catalyzed Regioselective Synthesis of Triazole Fused-1,5-Benzoxazocinones

Apr 03-Apr 09


Au-Catalyzed Synthesis of Thiopyrano[2,3-indoles Featuring Tandem Rearrangement and Hydroarylation

Gold(I)-Catalyzed Cyclization for the Synthesis of 8-Hydroxy-3- substituted Isocoumarins: Total Synthesis of Exserolide F

Rapid access to cyclopentadiene derivatives through gold-catalyzed cycloisomerization of ynamides with cyclopropenes by preferential activation of alkenes over alkynes

Azomethine-isocyanide [3+2] cycloaddition to imidazoles promoted by silver and DBU>

Silver-Catalyzed [2+1] Cyclopropenation of Alkynes with Unstable Diazoalkanes:N-Nosylhydrazones as Room-Temperature Decomposable Diazo Surrogates

Direct Reductive Amination of Aldehydes via Environmentally Benign Bentonite-Gold Nanohybrid Catalysis

Silver-Catalyzed Regio- and Stereoselective Thiocyanation of Haloalkynes: Access to (Z)-Vinyl Thiocyanates

Mar 27-Apr 03


Gold-Catalyzed Oxidative [2+2+1] Annulations of Aryldiazo Nitriles with Imines To Yield Polyarylated Imidazolium Salts

Synthetic Access Toward Cycloastragenol Glycosides

Synthesis of Propargyl-Functionalized NHC Gold Complexes

Formation of Gold(III) Alkyls from Gold Alkoxide Complexes

Mar 20-Mar 26


Platinum-Catalyzed Double Acylation of 2-(Aryloxy)pyridines via Direct C–H Activation

Asymmetric Total Synthesis of (−)-Aspidophylline A

Synthesis of Pentafluoroethyl Ethers by Silver-Mediated Oxidative Pentafluoroethylation of Alcohols and Phenols

Use of a Traceless Activating and Directing Group for the Construction of Trifluoromethylpyrazoles: One-Pot Transformation of Nitroolefins and Trifluorodiazoethane

Gold-Catalyzed Formal Cyclisation/Dimerization of Thiophene-Tethered Diynes

Photosensitizer-Free, Gold-Catalyzed C–C Cross-Coupling of Boronic Acids and Diazonium Salts Enabled by Visible Light

Mar 13-Mar 19

Yuk Fai

Silver-catalyzed decarboxylative bromination of aliphatic carboxylic acids

Silver-catalyzed regioselective fluorination of carbonyl directed alkynes: synthesis of α-fluoroketones

Silver-catalyzed cyclization of ortho-carbonylarylacetylenols for the synthesis of dihydronaphthofurans

On the gold-catalyzed generation of phenyl cations from 1,5-diynes

Gold-catalyzed intermolecular cyclocarboamination of ynamides with 1,3,5-triazinanes: en route to tetrahydropyrimidines

Gold catalysis: synthesis of spiro, bridged, and fused ketal natural products

TEMPO-catalyzed oxidative dimerization and cyanation of indoles for the synthesis of 2-(1H-indol-3-yl)-3-oxoindoline-2-carbonitriles

Mechanistic study on silver-catalyzed direct amination of unactivated C-H bond

Mar 06-Mar 12


Electrostatic Control of Regioselectivity in Au(I)-Catalyzed Hydroarylation

Gold(I)-Catalyzed Intramolecular Hydroamination of Unactivated Terminal and Internal Alkenes with 2-Pyridones

Silver-Catalyzed 1,3-Acyloxy Migration/Diels–Alder Reaction of 1,9-Dien-4-yne Esters to Partially Hydrogenated Isoquinolines

N1-Selective alkenylation of 1-sulfonyl-1,2,3-triazoles with alkynes via gold catalysis

Feb 27-Mar 05

Xu Ma

Silver-Catalyzed C(sp3)–H Chlorination

Synthesis of β-(1→2)-Linked 6-Deoxy-L-altropyranose Oligosaccharides via Gold(I)-Catalyzed Glycosylation of an ortho-Hexynylbenzoate Donor

Gold(I)-Catalyzed Enantioselective [2+2+2] Cycloadditions: An Expedient Entry to Enantioenriched Tetrahydropyran Scaffolds

Direct and Autocatalytic Reductive Elimination from Gold Complexes ([(Ph3P)Au(Ar)(CF3)(X)], X=F, Cl, Br, I): The Key Role of Halide Ligands

Gold-catalyzed highly regio- and enantioselective vinylcarbene insertion into O–H bonds of 2-pyridones

A new approach for the synthesis of tetrabenzimidazolium salt as a precursor for the tetra-N-heterocyclic carbene dinuclear silver(I) complex

Feb 13-Feb 19

Zhitong Zheng

Silver-Catalyzed Radical-Involved Cascade Cyclization of Diphenylphosphine with Cinnamamides: Access to 2-Phosphinoyl-3H-pyrrolo[1,2-a]indoles

In Vivo Gold Complex Catalysis within Live Mice

On the Gold-Catalyzed Generation of Vinyl Cations from 1,5-Diynes

Enantioselective Aza-Ene-type Reactions of Enamides with Gold Carbenes Generated from α-Diazoesters

Rationally Designed Blue Triplet Emitting Gold(III) Complexes Based on a Phenylpyridine-Derived Framework

Stereoselective Synthesis of a Ceramide Transporter Protein (CERT)-Dependent Ceramide-Trafficking Inhibitor, (1R,3S)-HPA-12, via Gold(I)-Catalyzed Cyclization of a Propargylic N-Hydroxylamine

Feb 06-Feb 12

Li Chen

Dihydrogen and Acetylene Activation by a Gold(I)/Platinum(0) Transition Metal Only Frustrated Lewis Pair

Drawing Catalytic Power from Charge Separation: Stereoelectronic and Zwitterionic Assistance in the Au(I)-Catalyzed Bergman Cyclization

Gold-Catalyzed [2,3]-Sigmatropic Rearrangement: Reaction of Aryl Allyl Alcohols with Diazo Compounds

One Lump or Two? A Plurality of Pathways in Gold(III)-Catalyzed Cyclization Transforming Propargyl Acetates to a Carene-like Bicyclo[4.1.0]heptane

Gold-Catalyzed Hydroarylation of N-Aryl Alkynamides for the Synthesis of 2-Quinolinones

Silver(I)-promoted insertion into X–H (X = Si, Sn, and Ge) bonds with N-nosylhydrazones

Gold-Catalysed Formal Cyclisation/Dimerization of Thiophene-Tethered Diynes

Aryne formation via the hexadehydro Diels-Alder reaction and their Ritter-type transformations catalyzed by a cationic silver complex

Gold-Oxazoline Complex-Catalyzed Cross-Dehydrogenative Coupling of Glycine Derivatives and Alkenes

Regioselective Direct C3-Phosphorylation of N-Sulfonylindoles under Mild Oxidative Conditions

Jan 30-Feb 05

Yuguang Wang

Photoinduced gold-catalyzed domino C(sp) arylation/oxyarylation of TMS-terminated alkynols with arenediazonium salts

Unexpected skeletal rearrangement in the gold(I)/silver(I)-catalyzed conversion of 7-aryl-1,6-enynes to bicyclo[3.2.0]hept-6-enes via hidden brønsted acid catalysis

Desulfinylation of Ag(I) sulfinyl mesoionic carbenes: preparation of C-unsubstituted Au(I)–1,2,3-triazole carbene complexes

Gold-catalyzed direct alkynylation of azulenes

Silver(I)-promoted cascade reaction of propargylic alcohols, carbon dioxide, and vicinal diols: thermodynamically favorable route to cyclic carbonates

Gold-catalyzed ring-expansion through acyl migration to afford furan-fused polycyclic compounds

A cationic unsaturated platinum(II) complex that promotes the tautomerization of acetylene to vinylidene

Silver-catalyzed phosphonylation of unprotected propargylic alcohols for the synthesis of allenylphosphoryl compounds

Jan 23-Jan 29


Silver-catalyzed [2+1] cyclopropenation of alkynes with unstable diazoalkanes: N-nosylhydrazones as room-temperature decomposable diazo surrogates

Desulfinylation of Ag(I) Sulfinyl Mesoionic Carbenes: Preparation of C-Unsubstituted Au(I)–1,2,3-Triazole Carbene Complexes

Gold-Catalyzed Regio- and Stereoselective Addition of Carboxylic Acids to Iodoalkynes: Access to (Z)-β-Iodoenol Esters and 1,4-Disubstituted (Z)-Enynyl Esters

Silver-Catalyzed Anti-Markovnikov Hydroxyfluorination of Styrenes

A Cationic Unsaturated Platinum(II) Complex that Promotes the Tautomerization of Acetylene to Vinylidene

Highly para-Selective C−H Alkylation of Benzene Derivatives with 2,2,2-Trifluoroethyl α-Aryl-α-Diazoesters

Gold-Catalyzed [3+2]/Retro-[3+2]/[3+2] Cycloaddition Cascade Reaction of N-Alkoxyazomethine Ylides

Gold(I) Fluorohalides: Theory and Experiment

Silver-Catalyzed Regio- and Stereoselective Thiocyanation of Haloalkynes: Access to (Z)-Vinyl Thiocyanates

The Gold-Catalyzed Hydroarylation of Alkynes with Electron-Rich Heteroarenes – A Kinetic Investigation and New Synthetic Possibilities

Late-Stage Diversification of Non-Steroidal Anti-Inflammatory Drugs by Transition Metal-Catalyzed C–H Alkenylations, Thiolations and Selenylations

Silver-Catalyzed Carbon-Phosphorus Functionalization for Polyheterocycle Formation

Gold-Catalyzed 1,4-Carbooxygenation of 3-En-1-ynamides with Allylic and Propargylic Alcohols via Non-Claisen Pathways

Sulfide and Sulfonyl Chloride as Sulfonylating Precursors for the Synthesis of Sulfone-Containing Isoquinolinonediones

Dual gold and photoredox catalysis: visible light-mediated intermolecular atom transfer thiosulfonylation of alkenes

Silver-catalyzed formal [3+2]-cycloaddition of α-trifluoromethylated methyl isocyanides: a facile stereoselective synthesis of CF3-substituted heterocycles

Silver-catalyzed radical carbofluorination of unactivated alkenes with acetic acid in aqueous solution

Mechanistic study on silver-catalyzed direct amination of unactivated C-H bond

Jan 16-Jan 22

Yubing Bai

Silver-mediated radical coupling reaction of isocyanides and alcohols/phenols in the presence of water: unprecedented hydration and radical coupling reaction sequence

Silver-catalyzed germinal aminofluorination of diazoketones with anilines and N-fluorobenzenesulphonimide

AgNO3-catalyzed direct C–H arylation of quinolones by oxidative decarboxylation of aromatic carboxylic acids

Jan 9-Jan 15


A 11-Steps Total Synthesis of Magellanine through a Gold(I)-Catalyzed Dehydro Diels–Alder Reaction

Oxidative Aza-Annulation of Enynyl Azides to 2-Keto/Formyl-1H-pyrroles

Diverse Pathways in Catalytic Reactions of Propargyl Aryldiazoacetates: Selectivity between Three Reaction Sites

Accessing alternative reaction pathways of the intermolecular condensation between homo-propargyl alcohols and terminal alkynes through divergent gold catalysis

Convenient synthesis of 6-alkyl phenanthridines and 1-alkyl isoquinolines via silver-catalyzed oxidative radical decarboxylation

Gold-Catalyzed Regiodivergent [2 + 2 + 2]-Cycloadditions of Allenes with Triazines

Gold-Catalyzed Unexpected Ring Transformation of Pyrimidodiazepine Derivatives

Jan 2-Jan 8


Understanding the Effect of α-Cationic Phosphines and Group 15 Analogues on π-Acid Catalysis

Anchoring Triazole-Gold(I) Complex into Porous Organic Polymer To Boost the Stability and Reactivity of Gold(I) Catalyst

Gold-catalyzed sequential annulations towards 3,4-fused bi/tri-cyclic furans involving a [3+2+2]-cycloaddition

An efficient approach to generate aryl carbenes: gold-catalyzed sequential activation of 1,6-diynes

Convenient synthesis of 6-alkyl phenanthridines and 1-alkyl isoquinolines via silver-catalyzed oxidative radical decarboxylation

Oxidative Divergent Bicyclizations of 1,n-Enynes through α-C(sp3)–H Functionalization of Alkyl Nitriles

Ag-Assisted Fluorination of Unprotected 4,6-Disubstituted 2-Aminopyrimidines with Selectfluor

Carbon(0)-Bridged Pt/Ag Dinuclear and Tetranuclear Complexes Based on a Cyclometalated Pincer Carbodiphosphorane Platform

Silver-catalysed tandem hydroamination and cyclization of 2-trifluoromethyl-1,3-enynes with primary amines: modular entry to 4-trifluoromethyl-3-pyrrolines

Silver-catalyzed one-pot synthesis of benzyl 2-alkynoates under ambient pressure of CO2 and ligand-free conditions


Advance in Au/Pt catalysis










before 2008


Liming Zhang
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Au/Ag/Pt catalysis


contact us: Prof. Liming Zhang office: 1631E PSB-N tel: (805) 893-7392 Email: zhang@chem.ucsb.edu Lab: 1612A PSB-N
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