Research Projects

Proteins

Aβ - References
  1. "Elucidating amyloid β-protein folding and assembly: A multidisciplinary approach" D. B. Teplow, N. D. Lazo, G. Bitan, S. Bernstein, T. Wyttenbach, M. T. Bowers, A. Baumketner, J.-E. Shea, B. Urbanc, L. Cruz, J. Borreguero, H. E. Stanley Acc. Chem. Res. 2006, 39, 635-645
  2. "Amyloid β-protein: Monomer structure and early aggregation states of Aβ42 and its Pro19 alloform" S. L. Bernstein, T. Wyttenbach, A. Baumketner, J.-E. Shea, G. Bitan, D. B. Teplow, M. T. Bowers J. Am. Chem. Soc. 2005, 127, 2075-2084
  3. "Amyloid β-protein monomer structure: A computational and experimental study" A. Baumketner, S. L. Bernstein, T. Wyttenbach, G. Bitan, D. B. Teplow, M. T. Bowers, J.-E. Shea Protein Sci. 2006, 15, 420-428
  4. "Structure of the 21-30 fragment of amyloid β-protein" A. Baumketner, S. L. Bernstein, T. Wyttenbach, N. D. Lazo, D. B. Teplow, M. T. Bowers, J.-E. Shea Protein Sci. 2006, 15, 1239-1247
  5. "Molecular dynamics simulations of Alzheimer’s β-amyloid protofilaments" N.-V. Buchete, R. Tycko, G. Hummer, J. Mol. Biol. 2005, 353, 804-821
  6. "Click peptides - Chemical biology-oriented synthesis of Alzheimer’s Disease-related amyloid β peptide (Aβ) analogues based on the O-acyl isopeptide method" Y. Sohma, Y. Kiso ChemBioChem 2006, 7, 1549-1557
  7. "A novel approach to Alzheimer's Disease therapy: Inhibition of Aβ42 oligomerization by C-terminal Aβ42 fragments" B. H. Monien, E. A. Fradinger, S. M. Spring, S. L. Bernstein, M. T. Bowers, G. Bitan J. Pept. Sci. 2006, 12, S1, 272